Kirigami-Inspired Brain Implants Record Neurons with Unmatched Precision

Scientists have created a flexible microelectrode array inspired by kirigami to record brain activity in primates. The device uses a spiral thread design that adapts to the brain's surface, reducing inflammation and improving long-term stability. Early tests show it can capture detailed neuronal signals with high precision.

The new array solves a key problem in brain-machine interfaces: the mismatch between rigid probes and soft, shifting brain tissue. Unlike traditional flat probes, these kirigami-inspired threads bend and stretch in three dimensions. They move with the brain's natural pulsations, avoiding strain and minimising damage.

The arrays are placed on the brain using a water-soluble hydrogel carrier, allowing quick and widespread deployment. Once in position, the stretchable threads float along the cortical surface, conforming to its contours. This flexibility prevents inflammation and gliosis, which often disrupt long-term recordings.

In tests with macaque monkeys, the arrays recorded activity from over 700 neurons at once. The high-fidelity signals enabled researchers to decode upper-limb movements with remarkable accuracy. The broad coverage also makes it easier to study complex neural circuits linked to behaviour.

The kirigami design ensures the device remains robust even when stretched or bent. It can reversibly deform without electrical failure or peeling, making it far more durable than older technologies.

This kirigami-based array offers a major step forward for brain-machine interfaces. Its ability to record from hundreds of neurons while adapting to brain movement could improve neuroprosthetics and neural research. The next phase will likely involve further testing in primates before potential human applications.